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portada Brain Glycogen Metabolism
Type
Physical Book
Publisher
Language
English
Pages
443
Format
Hardcover
Dimensions
23.4 x 15.6 x 2.5 cm
Weight
0.81 kg.
ISBN13
9783030274795

Brain Glycogen Metabolism

Arne Schousboe (Illustrated by) · Mauro Dinuzzo (Illustrated by) · Springer · Hardcover

Brain Glycogen Metabolism - Dinuzzo, Mauro ; Schousboe, Arne

New Book

£ 205.87

  • Condition: New
Origin: U.S.A. (Import costs included in the price)
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Synopsis "Brain Glycogen Metabolism"

This book aims to provide a state-of-the-art summary of what is currently known about brain glycogen metabolism, detailing the recent advances in our understanding of why glycogen is so critical for normal brain function. The role of glycogen in cellular neurophysiology remains largely unclear and its specific contribution to the energy demand of brain cells is still elusive.Glycogen is the sole cerebral glucose reserve and is emerging as a fundamental component of brain energy metabolism. Pharmacological or genetic manipulation of glycogen metabolism in the brain impairs memory formation and increases susceptibility to epileptic seizures and cortical spreading depression. Glycogen is also directly implicated in abnormal neuronal excitability and mental retardation that characterize brain disorders like Lafora disease and Pompe disease.

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