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portada Handbook of Her2-Targeted Agents in Breast Cancer
Type
Physical Book
Publisher
Author
Year
2014
Language
English
Pages
96
Format
Paperback
ISBN13
9781907673931
Edition No.
2013
Categories

Handbook of Her2-Targeted Agents in Breast Cancer

Ricardo H Alvarez; Javier Cortés; Leticia Mattos-Arruda; Mary Falzon; Angelica Fasolo; Michael Gandy; Luca Gianni; Nadia Harbeck; Martine Piccart; Stefania Zambelli; Dimitrios Zardavas (Author) · Springer · Paperback

Handbook of Her2-Targeted Agents in Breast Cancer - Ricardo H Alvarez; Javier Cortés; Leticia Mattos-Arruda; Mary Falzon; Angelica Fasolo; Michael Gandy; Luca Gianni; Nadia Harbeck; Martine Piccart; Stefania Zambelli; Dimitrios Zardavas

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Synopsis "Handbook of Her2-Targeted Agents in Breast Cancer"

​Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year.  Of these cases, approximately  15–25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes.  However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer  provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings.

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