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portada hepatic transport of organic substances
Type
Physical Book
Publisher
Year
2012
Language
English
Pages
435
Format
Paperback
Dimensions
24.4 x 17.0 x 2.3 cm
Weight
0.72 kg.
ISBN
3642742491
ISBN13
9783642742491

hepatic transport of organic substances

Ernst Petzinger (Illustrated by) · Rolf K. H. Kinne (Illustrated by) · Helmut Sies (Illustrated by) · Springer · Paperback

hepatic transport of organic substances - Petzinger, Ernst ; Kinne, Rolf K. H. ; Sies, Helmut

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Synopsis "hepatic transport of organic substances"

Hepatic cells are involved in the metabolization and elimination of a variety of endogenous and exogenous substances. They mediate the uptake, processing and subsequent secretion of biliary compounds, such as various drugs or hormones, and the passage of metabolites to be released into different blood compartments. To perform vectorial passages hepatocytes show a strong polarity with sites for endocytotic processes or specific carrier molecules, and a specified system of organelles for intracellular transport and sorting, metabolization and secretion of compounds. Several aspects, e.g. regulation, control and mechanisms of hepatic traffic are reported in detail - complemented by methodological approaches to analyse and monitor these processes.

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