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portada Mitochondrial Dysfunction: A Functional Medicine Approach to Aging and Diseases
Type
Physical Book
Illustrated by
Language
English
Pages
254
Format
Hardcover
Dimensions
27.9 x 21.6 x 1.6 cm
Weight
0.88 kg.
ISBN13
9781646465590

Mitochondrial Dysfunction: A Functional Medicine Approach to Aging and Diseases

John Binnington (Illustrated by) · Foster Academics · Hardcover

Mitochondrial Dysfunction: A Functional Medicine Approach to Aging and Diseases - Binnington, John

Physical Book

£ 128.39

  • Condition: New
Origin: U.S.A. (Import costs included in the price)
It will be shipped from our warehouse between Monday, June 24 and Wednesday, July 10.
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Synopsis "Mitochondrial Dysfunction: A Functional Medicine Approach to Aging and Diseases"

Mitochondria are double-membrane-bound organelles found in eukaryotic cells. They build cable-like structures and deliver energy to cells with the help of oxidative phosphorylation (OXPHOS) process. Aging causes a wide range of interrelated conditions and is also a leading cause of various human diseases. The age-associated changes in mitochondria are linked with deterioration in mitochondrial function. The accumulation of oxidative damage and mutations caused by reactive oxygen species (ROS), mitochondrial functionality, and DNA volume and integrity decline with age. Mitochondrial dysfunction includes an increase in oxidative damage and a reduction in oxidative capacity, and plays a significant role in biological aging. The accumulation of dysfunctional mitochondria occurs in all the tissues with aging, including brain, liver and skeletal muscle. These dysfunctional mitochondria are marked and removed through an autophagic process named mitophagy. Mitochondrial dysfunction occurs in many neurodegenerative diseases such as Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), Friedreich's ataxia (FRDA) and Alzheimer's disease (AD). This book explores all the important aspects of mitochondrial dysfunction and its impact on aging and diseases. Experts and students actively engaged in researches on mitochondrial dysfunction will find it full of crucial and unexplored concepts.

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