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Actin Polymerization in Apicomplexan: A Structural, Functional and Evolutionary Analysis
Kale, Avinash (Author)
·
Springer
· Hardcover
Actin Polymerization in Apicomplexan: A Structural, Functional and Evolutionary Analysis - Kale, Avinash
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Origin: U.S.A.
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Synopsis "Actin Polymerization in Apicomplexan: A Structural, Functional and Evolutionary Analysis"
This book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements. The book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CPα and CPβ), cyclase-associated protein (CAP) and coronin 13-24 as potential drug targets against malaria. As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design. Lastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics.
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All books in our catalog are Original.
The book is written in English.
The binding of this edition is Hardcover.
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