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portada Matrix Metalloproteinases and Timps (Protein Profiles)
Type
Physical Book
Publisher
Year
2000
Language
English
Pages
240
Format
Paperback
ISBN
0198502680
ISBN13
9780198502685
Edition No.
2

Matrix Metalloproteinases and Timps (Protein Profiles)

J. F. Woessner; Fred Woessner; Hideaki Nagase (Author) · Oup Oxford · Paperback

Matrix Metalloproteinases and Timps (Protein Profiles) - J. F. Woessner; Fred Woessner; Hideaki Nagase

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Synopsis "Matrix Metalloproteinases and Timps (Protein Profiles)"

The matrix metalloproteinases (MMPs) are a large family of enzymes that breakdown different components of the extracellular matrix. Their catalytic activity is dependent a metal ion, usually zinc. This issue of the Protein Profiles covers the sequence information, three-dimensional structures, activation, protein substrates, specificity requirements, inhibition, and biological roles of all the currently identified MMPs. The action of these enzymes must be carefully regulated. One way the cell does this, is by releasing inhibitory molecules known as tissue inhibitors of metalloproteinases (TIMPs). This volume contains information on the sequences, three-dimensional structures, and biological roles of the 4 known classes of TIMP. Matrix metalloproteinases will therefore be an invaluable source of data for all researchers interested in MMPs and TIMPs.

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