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portada physiologically based pharmacokinetic modeling: science and applications
Type
Physical Book
Pages
420.00
ISBN
0471478148
ISBN13
9780471478140
Categories

physiologically based pharmacokinetic modeling: science and applications

Micaela Reddy, R. S. Yang, Melvin E. Andersen (Author) · wiley-interscience · Physical Book

physiologically based pharmacokinetic modeling: science and applications - micaela reddy, r. s. yang, melvin e. andersen

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Synopsis "physiologically based pharmacokinetic modeling: science and applications"

this book describes the development of pbpk modeling for toxic compounds over the past eight decades and the current uses of these models.  the book provides background on the basics of pbpk modeling. following an introductory chapter on pbpk modeling, a series of chapters reviews pbpk model results for various classes of compounds with coverage of historical development, specific modeling challenges, and current practices. comments describe the use of these pbpk models to support pharmacodynamic modeling for toxic responses and future directions for modeling.

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