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portada Protein Homeostasis Diseases: Mechanisms and Novel Therapies
Type
Physical Book
Publisher
Language
English
Pages
450
Format
New
ISBN13
9780128191323
Edition No.
1

Protein Homeostasis Diseases: Mechanisms and Novel Therapies

Pey Angel L. (Author) · Academic Press · Nuevo

Protein Homeostasis Diseases: Mechanisms and Novel Therapies - Pey Angel L.

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Synopsis "Protein Homeostasis Diseases: Mechanisms and Novel Therapies"

Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-function, and how natural ligands can restore protein function and homeostasis in genetic diseases. Applied chapters provide guidance on employing high throughput sequencing and screening methodologies to develop pharmacological chaperones and repurpose approved drugs to treat protein homeostasis disorders.

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The book is written in English.
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