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The Chemistry of β-Lactams
Page, M. I. (Author)
·
Springer
· Paperback
The Chemistry of β-Lactams - Page, M. I.
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Synopsis "The Chemistry of β-Lactams"
It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
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