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Cancer Through the Lens of Evolution and Ecology
Somarelli Jason A.,Johnson Norman A. (Author)
·
Crc Press
· Paperback
Cancer Through the Lens of Evolution and Ecology - Somarelli Jason A.,Johnson Norman A.
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Synopsis "Cancer Through the Lens of Evolution and Ecology"
New cancer cells exist an ever-changing "ecology" and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2) how scarce resources influence cancer therapy resistance; 3) how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4) how cancer cells parallel niche construction theory; 5) how changing fitness landscapes enable cancer growth; and 6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms.Key Features Bridges disciplines exemplifying the ways disparate fields create new perspectives when integrated. Offers insights from leading scholars in cancer biology, ecology and evolutionary biology. Provides a timely recognition by oncologists that evolutionary paradigms are crucial for breakthroughs in cancer treatment. Integrates basic and applied sciences of oncology and evolutionary biology.
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All books in our catalog are Original.
The book is written in English.
The binding of this edition is Paperback.
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