Name: Role of Tribulus Terrestris Against Acetaminophen-Induced Liver Damage: The Promise of Tribulus Terrestris l. In Liver Protection: A Mechanistic Approach in Acetaminophen-Induced Liver Damage
Price: 9.70 GBP
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Author: Javed Akhtar Ansari
ISBN: 9783659280948

portada Role of Tribulus Terrestris Against Acetaminophen-Induced Liver Damage: The Promise of Tribulus Terrestris l. In Liver Protection: A Mechanistic Approach in Acetaminophen-Induced Liver Damage

Type

Physical Book

Publisher

Lap Lambert Academic Publishing

Author

Javed Akhtar Ansari

Synopsis "Role of Tribulus Terrestris Against Acetaminophen-Induced Liver Damage: The Promise of Tribulus Terrestris l. In Liver Protection: A Mechanistic Approach in Acetaminophen-Induced Liver Damage"

Problems related to liver such as acute or chronic inflammation, toxin-/drug-induced hepatitis, cirrhosis and hepatitis are very common today due to our exposure to different environmental pollutants like chemicals, toxins, viruses etc. For centuries, many herbs have been used as natural medications for the prevention and/or treatment of liver diseases. Thus, the aim of the present study was to evaluate the role of Tribulus terrestris Linn. on acetaminophen-induced liver damage in rats. The rats were divided into five groups of 6 rats each for seven days oral administration. The methanolic extract of Tribulus terrestris L. produced significant hepatoprotective effects as evidenced by decreased serum enzyme activities, SGOT, SGPT, ALP, serum bilirubin, increased total protein. Histopathological architecture of the liver in test group was identical to the reference group. Based on our present findings, it can be concluded that Tribulus terrestris Linn. protects the liver from acetaminophen-induced hepatic damage by stabilizing effect on the plasma membrane as was reported in the case of Silymarin. Responsible leads for the present hepatoprotective studies are flavonoids.