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portada the serotonin receptors: from molecular pharmacology to human therapeutics
Type
Physical Book
Illustrated by
Publisher
Year
2010
Language
English
Pages
618
Format
Paperback
Dimensions
22.9 x 15.2 x 3.6 cm
Weight
0.92 kg.
ISBN
1617376477
ISBN13
9781617376474

the serotonin receptors: from molecular pharmacology to human therapeutics

Bryan L. Roth (Illustrated by) · Humana · Paperback

the serotonin receptors: from molecular pharmacology to human therapeutics - Roth, Bryan L.

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£ 233.02

  • Condition: New
Origin: U.S.A. (Import costs included in the price)
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Synopsis "the serotonin receptors: from molecular pharmacology to human therapeutics"

A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.

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